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KMID : 0378120030300020253
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Chungnam Medical Journal
2003 Volume.30 No. 2 p.253 ~ p.256
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Evaluation of Usefulness of Autoimmunoanalyzer Architech
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Kwon Kye-Chul
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Abstract
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The newly developed immunoassay analyzer, Architect(Abbott, USA) has been chosen as a method of tumor and viral markers because it is easily applicable to TLA(total laboratory automation)system.
Laboratory tests can be performed at TLA system in some large hospitals for rapid, accurate results and decreased labor.
The linearity, accuracy, precision and correlation study with conventional EIA method was performed to evaluate the usefulness of Architect immunoanalyzer concerning HCV test.
The results were as follows :
1. Within run coefficient of variation(CV) at 20 runs with control serum of HCV was 2.07%,
2. Between run CV at 20 days with control serum of HCV was 3.73%.
3. The percentage of variation in HCV was 2.86% to evaluate accuracy with the control serum measured 20 times.
4. The linearity of HCV was evaluated with the control serum diluted 100:0, 80:20, 60:40, 40:60, 0:100. The regression equation of those were Y=0.361X-0.190(R=0.995).
5. The correlation of the HCV with conventional EIA was Y=0.867X-0.102(R=0.948).
The architect immunoanalyzer was adequate to perform viral marker tests in TLA system because of its high precision, good accuracy, linearity and high correlation with conventional EIA.
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KEYWORD
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Immunoanalyzer, Architect, TLA
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